Pharma Tech Outlook: Pharma Tech Magazine

Minakem: Developing Fine Chemicals for the Life Sciences

Top 10 CMO’s in Europe - 2020


The contract manufacturing sector is witnessing significant growth as the global pharmaceutical expands at a rapid rate. More and more companies are outsourcing drug manufacturing to contract manufacturing organisations (CMOs) to streamline production and reduce risks. The rising demand for generic medicines and the capital-intensive nature of the business has necessitated collaboration with efficient CMOs for clinical and commercial stage manufacturing. Also, it allows pharmaceutical organisations to focus their resources on research and development, thus, enabling them to gain a competitive edge in the pharmaceutical market.

In order to assist pharmaceutical companies in the daunting task of finding accomplished CMOs, we have crafted this issue of Pharma Tech Outlook. In this edition, we have compiled a list of the leading CMOs in Europe that are making significant contributions to the pharmaceutical sector. The companies listed here showcase extensive business knowledge and exhibit competence in delivering cutting-edge technologies and solutions that meet the needs of the customers.

We present to you Pharma Tech Outlook’s “Top 10 CMOs in Europe – 2020.”

    Top CMO’s in Europe

  • Specialises in supercritical fluid extraction, which allows the recovery of valuable lipids from plant material. And, unlike conventional solvent extraction methods, there are no harmful compounds produced, even the carbon dioxide used is extracted from the atmosphere and recirculated after use. Aromtech’s extraction process uses an aseptic processing medium without thermal or oxidative stress, which preserves the delicate, valuable fatty acids and fat-soluble nutrients in their natural and bioactive form. Moreover, Aromtech’sstate-of-the-art manufacturing facility guarantees that the best possible standards can be met in terms of product purity and safety. Being practically effluent-free without the use of any chemicals, the facility meets the most stringent criteria for environmental compliance and workplace safety

  • The CMO maintains an entirely multi-purpose, aseptic PFS and vial filling line for liquid and lyophilized injectable products. Housed at the company’s GMP-certified facility at the Brightlands Chemelot Research Campus in the Netherlands, the aseptic filling line operates in a class ‘A’ isolator, which guarantees an aseptic production process, thus ensuring protection for both product and operator. The filling line, offers a fully-automated method for filling and closing of syringes and vials. The line also contains a highly special lyophiliser able to handle high potency compounds and flammable liquids. The company is primarily engaged in the development, licensing, and manufacturing of registered and non-registered pharmaceutical products, and investigational medicinal products, along with laboratory services for the pharmaceutical, biotech, and medical device industry

  • Flamma provides a stable and secure supply chain for active pharmaceutical ingredients (APIs), new chemical entities (NCE), and registered starting materials (RSM) utilizing its four state-of-the-art cGMP manufacturing facilities complete with research and development (R&D) staff and labs. In addition, the company provides specialty compounds and advanced intermediates for the nutraceutical and cosmetic industries. The company provides the expertise for assisting its clients in early phase development as well as large-scale manufacturing. Flamma prides itself with the customer service they provide working with clients to solve problems. Some of Flamma’s capabilities include custom synthesis, process development and optimization, analytical validation, ICH stability studies, calorimetry studies, and safety risk assessments

  • A fully integrated development partner and commercial manufacturer of APIs, HPAPIs, key intermediates, and building blocks for pharmaceutical companies. The tagline of the company, ‘Chemistry for life,’ summarises the core mission of MINAKEM, i.e., supporting its clients to deliver better and affordable medicines to the patients in a time-efficient manner. MINAKEM offers a combination of innovative development and manufacturing solutions through a wide range of flexible assets, specialised technologies, and advanced process capabilities for the synthesis of intermediates, APIs, and HPAPIs at all production scales

  • 3P Biopharmaceuticals

    3P Biopharmaceuticals

    3P Biopharmaceuticals is a leading European GMP Contract Manufacturing Organization (CMO) specialized in the process development and cGMP manufacture of Biologics and Cell Therapy products. Custom manufacturing of Biologics from mammalian, yeast, and bacterial systems are developed from proof of concept to commercial stages being able to adapt to regulatory requirements for every phase. An integral and complete bioproduction service, with a wide range of related services, is offered by 3P Biopharmaceuticals. The company specializes in biotechnology, recombinant proteins, advanced therapies, biosimilars, biologics, biotech, cell therapy, mammalian, cell banks, characterization, stability studies, manufacturing, regulatory affairs, quality assurance, DMA, Upstream, Downstream, and Purification

  • Celonic Group

    Celonic Group

    Celonic Group is a privately owned CDMO with two state-of-the-art sites located at Basel, Switzerland, and Heidelberg, Germany. Celonic’s services include the development of cell lines, production processes, as well as non-GMP and GMP manufacturing of biopharmaceutical drug substances and drug products. To complement their services with cell line development, Celonic uses its proprietary CHOvolution cell line technology and the human cell line GEX for a natural or difficult target. Being part of the JRS Pharma family, Celonic is a firm believer in creating win-win value propositions for the clients, mitigating risks by mutually-beneficial business models

  • CordenPharma


    CordenPharma is your full-service partner in the Contract Development & Manufacturing (CDMO) of APIs, Drug Products, and associated Packaging Services. Through a network of cGMP facilities across Europe and the US organized under five technology platforms – Peptides, Lipids & Carbohydrates – Injectables - Highly Potent & Oncology - Small Molecules - Antibiotics - CordenPharma experts translate complex ideas, processes, and projects at any stage of development into high-value products. The company was founded in 2006. With a team of experts specializes in offering Contract Development & Manufacturing Organization (CDMO), Highly Potent APIs, Formulations, Drug Products, Peptides, Lipids, Carbohydrates, Injectables, Small Molecule APIs & Excipients, Antibiotic & Oncology APIs & Drug Products, and Primary & Secondary Packaging

  • Lonza


    With above 15,000 employees in more than 100 locations around the world, Lonza is a global leader in life sciences. They achieved global sales of 5.5 CHF billion. The company has applied its industry knowledge to pioneer cell therapy and the medicines of tomorrow. Their work enables customers to protect millions of people from illness and disease. The company's most exceptional scientific solution is talented people working together, devising commitment and ideas that help their customers to help people

  • Pharmex


    Headquartered in Alcobendas, Madrid, Pharmex Advanced Laboratories is a Spanish pharmaceutical company founded in August 2016 through the acquisition of a state-of-the-art industrial unit from Laboratorios Pérez Giménez. Pharmex is concentrating its efforts on the development, manufacturing, and marketing of quality Rx, OTC, and Medical Devices Globally with a strong emphasis in regions like MEA and LatAm. Pharmex is present in the Spanish market with its sales force and distributes to pharmacies and wholesalers under its brand. With a Nutrition business unit, specialized in infant formulas and cereals (Tebramil ®), Pharmex aspires to be a lead provider in this field. Pharmex is focused on guaranteeing access to health with the highest quality standards based on the know-how of our technical staff, the company's vision, and our dynamic management team

  • PMC Isochem

    PMC Isochem

    Founded in 2017, PMC Isochem is a custom pharmaceutical manufacturing company. They are a fully integrated business that does research, product/process development, pilot scale and full plant-scale production of drug intermediates regulatory approvals, and active pharma ingredients (APIs) for big pharmaceutical companies globally to serve the needs of Oncology, Cardiovascular, Infectious, Gastro-Intestinal, Neurology, and rare diseases. These facilities, with a combined footprint of over 40 acres, are located at three sites -- Gennevilliers, Pithiviers, and Vert-Le-Petit -- within a 60 miles radius of Paris. The facilities are all cGMP US-FDA audited plants for manufacturing pharmaceutical products